Azelastine is an active ingredient that has been used for decades against hay fever. Many over-the-counter nasal sprays contain azelastine. A new study from Saarland University now provides indications that azelastine nasal sprays can do more than just relieve allergies.
While vaccinations remain the most important protective measure against a severe course of COVID-19, there are so far hardly any medications that can prevent infection with the corona viruses. Earlier laboratory studies had shown that azelastine also has antiviral properties – it can therefore directly inhibit viruses. The researchers from Homburg now wanted to investigate whether azelastine nasal sprays can contribute to the prevention of SARS-CoV-2 infections in healthy adults.
The result was clear:
Azelastine not only blocks histamine (which triggers symptoms in allergies), but also seems to slow down several viruses, including SARS-CoV-2, influenza and rhinoviruses. It influences certain docking sites of the viruses in the nasal mucosa and thus makes it more difficult for them to enter the cells.
Why this is important
Even with a high vaccination rate, it is still possible to become infected with corona. A well-tolerated, over-the-counter nasal spray could help to further reduce the risk in everyday life.
However, the researchers emphasize that the results still need to be verified in larger studies.
An already established allergy spray could help to better protect against respiratory viral infections – including COVID-19. I recommend the use of azelastine nasal sprays to my patients when there is an increased risk of becoming infected with corona viruses. For example when another family member is ill, before large events such as concerts, before traveling by train or airplane, or if you frequently use public transport during the cold season.
The content of this blog/newsletter is provided for general informational purposes only and does not replace personal medical advice, diagnosis, or treatment. The information presented here should therefore not be used as the sole basis for making health-related decisions. If you experience any medical complaints, you should in any case seek professional medical advice.
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